Ginkgo Biloba

Ginkgo Biloba

银杏 (Yín Xìng) · Ginkgo biloba

One of the oldest living tree species. Widely studied for improving blood circulation to the brain, supporting memory, and protecting against cognitive decline.

근거 점수
10/10
안전성
주의하여 사용

효능

주요 효과

Improves blood circulation to the brain

Established mechanism — increases cerebral blood flow in clinical imaging studies

May slow cognitive decline in dementia

Large trials (GEM, GuidAge) show modest benefit for existing cognitive impairment

Reduces symptoms of peripheral artery disease

Meta-analysis shows improved walking distance in intermittent claudication

May help tinnitus and vertigo

Some positive trials though overall evidence is mixed

복용 방법

일반 용량: 120-240mg standardized extract daily (EGb 761 — 24% flavone glycosides, 6% terpene lactones)
형태: standardized extract capsule, tablet, liquid extract
복용 시간: Split into 2-3 doses. Effects take 4-6 weeks to appear. Use the standardized extract — raw leaf tea is less effective and potentially toxic
EGb 761 is the specific extract used in most clinical trials (Tanakan/Tebonin brand)

안전성 및 상호작용

가능한 부작용

  • Headache
  • Digestive upset
  • Dizziness
  • Allergic skin reactions (rare)

사용 금지 대상

  • Bleeding disorders
  • 2 weeks before surgery
  • Seizure disorders (may lower threshold)

약물 상호작용

  • Blood thinners (warfarin, aspirin, NSAIDs) — increased bleeding risk
  • Anticonvulsants — may reduce effectiveness
  • SSRIs — rare reports of serotonin syndrome
  • Diabetes medications — may affect blood sugar

전통적 사용

The ginkgo tree is a living fossil — 270 million years old. In TCM, the seed (Bai Guo) is used more than the leaf. Seeds astringe the lungs, stop wheezing, and reduce vaginal discharge. The leaf extract is primarily a modern Western application developed from the 1960s onward.

현대 연구

Over 5,700 studies. The most studied herbal supplement for cognitive function. Active compounds: ginkgolides (PAF antagonists improving circulation) and bilobalide (neuroprotective). Evidence is strongest for existing cognitive impairment rather than prevention in healthy adults.

PubMed에서 연구 보기

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