Ginkgo Biloba

Ginkgo Biloba

银杏 (Yín Xìng) · Ginkgo biloba

One of the oldest living tree species. Widely studied for improving blood circulation to the brain, supporting memory, and protecting against cognitive decline.

エビデンススコア
10/10
安全性
注意して使用

効能

主な効果

Improves blood circulation to the brain

Established mechanism — increases cerebral blood flow in clinical imaging studies

May slow cognitive decline in dementia

Large trials (GEM, GuidAge) show modest benefit for existing cognitive impairment

Reduces symptoms of peripheral artery disease

Meta-analysis shows improved walking distance in intermittent claudication

May help tinnitus and vertigo

Some positive trials though overall evidence is mixed

飲み方

一般的な用量: 120-240mg standardized extract daily (EGb 761 — 24% flavone glycosides, 6% terpene lactones)
剤形: standardized extract capsule, tablet, liquid extract
タイミング: Split into 2-3 doses. Effects take 4-6 weeks to appear. Use the standardized extract — raw leaf tea is less effective and potentially toxic
EGb 761 is the specific extract used in most clinical trials (Tanakan/Tebonin brand)

安全性と相互作用

起こりうる副作用

  • Headache
  • Digestive upset
  • Dizziness
  • Allergic skin reactions (rare)

使用禁忌

  • Bleeding disorders
  • 2 weeks before surgery
  • Seizure disorders (may lower threshold)

薬物相互作用

  • Blood thinners (warfarin, aspirin, NSAIDs) — increased bleeding risk
  • Anticonvulsants — may reduce effectiveness
  • SSRIs — rare reports of serotonin syndrome
  • Diabetes medications — may affect blood sugar

伝統的な使用法

The ginkgo tree is a living fossil — 270 million years old. In TCM, the seed (Bai Guo) is used more than the leaf. Seeds astringe the lungs, stop wheezing, and reduce vaginal discharge. The leaf extract is primarily a modern Western application developed from the 1960s onward.

現代の研究

Over 5,700 studies. The most studied herbal supplement for cognitive function. Active compounds: ginkgolides (PAF antagonists improving circulation) and bilobalide (neuroprotective). Evidence is strongest for existing cognitive impairment rather than prevention in healthy adults.

PubMedで研究を見る

Where to Buy

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