Ashwagandha

Ashwagandha

南非醉茄 (Nán Fēi Zuì Qié) · Withania somnifera

An Ayurvedic adaptogen now widely used globally. Strong clinical evidence for reducing stress and anxiety, improving sleep quality, and boosting testosterone in men.

エビデンススコア
7.5/10
安全性
ほとんどの成人に安全

効能

主な効果

Significantly reduces stress and anxiety

Meta-analysis of 12 RCTs shows significant reduction in stress scores (Hamilton Anxiety Scale)

Improves sleep quality

Clinical trials show improved sleep onset, quality, and efficiency vs placebo

Increases testosterone in men

Multiple RCTs show 15-40% increase in testosterone with 8-12 weeks supplementation

Enhances athletic performance

Trials show improved VO2max, strength, and recovery in athletes

飲み方

一般的な用量: 300-600mg root extract daily (standardized to 5%+ withanolides)
剤形: capsule, powder (churna), liquid extract, gummies
タイミング: Take with meals. For sleep, take in the evening. For stress/energy, take in the morning or split doses
KSM-66 and Sensoril are the most clinically studied branded extracts

安全性と相互作用

起こりうる副作用

  • Mild drowsiness (can be beneficial for sleep)
  • Digestive upset if taken on empty stomach
  • Rare: thyroid stimulation

使用禁忌

  • Hyperthyroidism (may increase thyroid hormones)
  • Autoimmune conditions (stimulates immune system)
  • Pregnancy
  • Scheduled surgery

薬物相互作用

  • Thyroid medications — may potentiate
  • Sedatives/benzodiazepines — additive drowsiness
  • Immunosuppressants — may counteract

伝統的な使用法

In Ayurveda, ashwagandha is a rasayana (rejuvenative). Its name means 'smell of the horse' — referring to both its scent and the horse-like vitality it provides. Used for debility, stress, insomnia, and reproductive health for over 3,000 years.

現代の研究

One of the most clinically studied adaptogens. Withanolides modulate cortisol, GABA, and serotonin pathways. The root extract (not leaf) is preferred for most applications. Over 1,900 studies on PubMed.

PubMedで研究を見る

Where to Buy

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