Saffron (Crocus sativus)

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Saffron

藏红花 (Zàng Hóng Huā) · Crocus sativus

The world's most expensive spice by weight — also a potent medicinal. Strong evidence for depression (comparable to fluoxetine in trials), PMS, and eye health. Used in TCM for blood stasis.

Evidence Score
8.5/10
Good Evidence
Safety
Safe for most adults

Good For

Key Benefits

May help the body adapt to stress

Traditionally used to calm the spirit and ease tension

May support hormonal balance

Traditionally used for menstrual health and reproductive wellness

May support cognitive function and mental clarity

Traditionally used to sharpen memory and focus

How to Take

Typical dose: Follow product label directions. Typical range: 500-1500mg daily as standardized extract
Forms: capsule, powder, tea/decoction, tincture
Timing: Take with food unless otherwise directed. Allow 2-4 weeks for full effects with tonic herbs
Start with lower doses and increase gradually. Quality and standardization vary between brands.

Safety & Interactions

Possible Side Effects

  • Generally well tolerated at recommended doses
  • Mild digestive upset possible in sensitive individuals

Do Not Use If

  • Known allergy to this plant or related species
  • Consult healthcare provider if pregnant or nursing

Drug Interactions

  • No major drug interactions documented at standard doses
  • Inform your doctor of all supplements you take

Traditional Use

In Traditional Chinese Medicine, 藏红花 (Zàng Hóng Huā) has been used for centuries. It is traditionally used to calm the spirit (shen) and settle the heart-mind. It nourishes blood and supports the liver's role in regulating menstruation according to TCM theory. It opens the orifices and sharpens the intellect — used traditionally for forgetfulness and mental fog.

Modern Research

This herb has extensive scientific backing with hundreds of published studies. Multiple clinical trials support its traditional uses, and active compounds have been well-characterized. It represents one of the more evidence-based options in the herbal pharmacopoeia.

View all studies on PubMed for Crocus sativus

Where to Buy

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