Image: Wikimedia Commons, CC BY-SA
Perilla Leaf (Zi Su Ye)
紫苏叶 (Zǐ Sū Yè) · Perilla frutescens
The shiso leaf of Japanese cuisine. In TCM releases the exterior for colds, calms nausea, and resolves seafood poisoning. Rich in rosmarinic acid with anti-allergic effects.
Good For
Key Benefits
May support immune system function
Traditionally used to strengthen defensive qi and resistance to illness
May support healthy digestive function
Traditionally used to harmonize the stomach and intestines
How to Take
Safety & Interactions
Possible Side Effects
- Generally well tolerated at recommended doses
- Mild digestive upset possible in sensitive individuals
Do Not Use If
- Known allergy to this plant or related species
- Consult healthcare provider if pregnant or nursing
Drug Interactions
- No major drug interactions documented at standard doses
- Inform your doctor of all supplements you take
Traditional Use
In Traditional Chinese Medicine, 紫苏叶 (Zǐ Sū Yè) has been used for centuries. TCM practitioners use it to reinforce the body's defensive energy (wei qi). It supports the spleen and stomach — the foundation of post-natal qi production in TCM theory.
Modern Research
Moderate research exists for this herb, including some clinical trials and substantial preclinical data. While not as extensively studied as top-tier herbs, the evidence supports several traditional uses. More human trials would strengthen the evidence base.
View all studies on PubMed for Perilla frutescens →Where to Buy
Affiliate links — purchases support this free resource.