Raw He Shou Wu

生何首乌 (Shēng Hé Shǒu Wū) · Polygonum multiflorum (raw)

The unprocessed form — used as a laxative and for detoxification in TCM. More toxic than the prepared form. Associated with liver injury in some case reports. Use only under professional guidance.

Evidence Score
4/10
Preliminary
Safety
Significant risks

Good For

Key Benefits

May support healthy digestive function

Traditionally used to harmonize the stomach and intestines

How to Take

Typical dose: Follow product label. Often taken as tea (3-5g dried herb steeped 10 min) or 500-1000mg extract with meals
Forms: capsule, powder, tea/decoction
Timing: Take with food unless otherwise directed. Allow 2-4 weeks for full effects with tonic herbs
Start with lower doses and increase gradually. Quality and standardization vary between brands.

Safety & Interactions

Possible Side Effects

  • Significant side effects possible even at normal doses
  • Liver toxicity reported in some cases
  • Narrow therapeutic window — dose-dependent toxicity

Do Not Use If

  • Do not self-medicate — professional supervision required
  • Pregnancy and breastfeeding — strictly avoid
  • Liver or kidney disease
  • Children

Drug Interactions

  • Multiple serious drug interactions possible
  • May dangerously potentiate blood thinners, immunosuppressants, or sedatives
  • Must inform doctor before use

Traditional Use

In Traditional Chinese Medicine, 生何首乌 (Shēng Hé Shǒu Wū) has been used for centuries. It supports the spleen and stomach — the foundation of post-natal qi production in TCM theory.

Modern Research

Research is still emerging for this herb. Most evidence comes from animal studies, in-vitro experiments, and traditional use records. Limited clinical trial data is available. The herb shows promise but requires more rigorous human studies to confirm efficacy.

View all studies on PubMed for Polygonum multiflorum (raw)

Where to Buy

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