Resveratrol (Polygonum cuspidatum)

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Resveratrol

虎杖 (Hǔ Zhàng) · Polygonum cuspidatum

Famous from red wine, but the primary supplement source is actually Hu Zhang (Japanese knotweed) — a TCM herb. Studied extensively for anti-aging and cardiovascular protection.

Evidence Score
5.5/10
Moderate
Safety
Safe for most adults

Good For

Key Benefits

May provide antioxidant protection

Traditionally associated with healthy aging and vitality

May support cognitive function and mental clarity

Traditionally used to sharpen memory and focus

How to Take

Typical dose: Follow product label directions. Typical range: 500-1500mg daily as standardized extract
Forms: capsule, powder, tea/decoction
Timing: Take with food unless otherwise directed. Allow 2-4 weeks for full effects with tonic herbs
Start with lower doses and increase gradually. Quality and standardization vary between brands.

Safety & Interactions

Possible Side Effects

  • Generally well tolerated at recommended doses
  • Mild digestive upset possible in sensitive individuals

Do Not Use If

  • Known allergy to this plant or related species
  • Consult healthcare provider if pregnant or nursing

Drug Interactions

  • No major drug interactions documented at standard doses
  • Inform your doctor of all supplements you take

Traditional Use

In Traditional Chinese Medicine, 虎杖 (Hǔ Zhàng) has been used for centuries. It is considered a longevity tonic — nourishing the fundamental essence (jing) and supporting the kidneys. It opens the orifices and sharpens the intellect — used traditionally for forgetfulness and mental fog.

Modern Research

Research is still emerging for this herb. Most evidence comes from animal studies, in-vitro experiments, and traditional use records. Limited clinical trial data is available. The herb shows promise but requires more rigorous human studies to confirm efficacy.

View all studies on PubMed for Polygonum cuspidatum

Where to Buy

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